Vicuna
.Nanobody design software.
Predict binding for nanobody–antigen pairs, and run virtual screens across natural repertoires or your own designs — to surface the binders worth making before they reach the bench.
From a target to a ranked shortlist.
Vicuna brings binding prediction and virtual screening into one loop, so your team spends bench time only on nanobodies that have already earned it.
Binding prediction
Score nanobody–antigen pairs and rank candidates by predicted binding, before committing to synthesis.
Virtual screening
Screen large natural nanobody repertoires against your target in silico to find promising binders fast.
De novo design
Generate and optimize new nanobody designs, then score them through the same binding model.
Developability screening
Flag aggregation, solubility, and stability liabilities early — the failures that usually surface late.
See the liabilities before you make the molecule.
Every candidate gets a profile across the properties that decide whether a binder survives manufacturing and the clinic — consistent, comparable, and ready to triage.
- Binding affinity
- Specificity
- Thermal stability
- Aggregation risk
- Solubility
Most nanobody programs don't fail at the idea. They fail at developability — late, and expensively.
Design, in a tight cycle.
Vicuna is built to run with your lab, not instead of it — each round of bench data sharpens the next round of design.
Assemble
Start from natural nanobody repertoires or your own de novo designs.
Predict
Score nanobody–antigen binding and developability in silico.
Screen
Rank, triage, and select the shortlist worth synthesizing.
Refine
Feed bench results back in to sharpen the next round.
Bring Vicuna into your pipeline.
We're partnering with a small number of teams. Tell us about your target and we'll set up access and a walkthrough.